2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]- (9CI) - Names and Identifiers
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]- (9CI) - Physico-chemical Properties
Molecular Formula | C21H22O9
|
Molar Mass | 418.4 |
Density | 1.528 |
Melting Point | 230-232℃ |
Boling Point | 743.5±60.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | Powder |
pKa | 7.36±0.35(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice. |
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]- (9CI) - Reference
Reference Show more | 1. Zhou Yuemei, Feng Chao, Shi Yuhua, et al. Study on HPLC fingerprint of licorice extract and determination of multi-index components [J]. China Modern Applied Pharmacy, 2020, v.37(09):26-31. 2. Li Shujuan, Li Hongjun, Lu Xiaodong, Yao Caihong, Zhou Sha. Study on the interaction between two flavonoids and human serum albumin [J]. Guangzhou chemical industry, 2020,48(19):40-42. 3. [IF = 2.629] Li Tingting et al."Quality Assessment of Licorice Based on Quantitative Analysis of Multicomponents by Single Marker Combined with HPLC Fingerprint."Evid-Based Compl Alt. 2021;2021:8834826 4. [IF=1.885] Xia Wenxin et al."Study on the Spectrum-Effect Relationship of the Traditional Effect of Saponins in Glycyrrhiza uralensis Fisch."Int J Anal Chem. 2021;2021:6617033 |
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]- (9CI) - Introduction
Neoisoliquitin is a natural liquiritin compound with the chemical name Glycyrrhizin.
Nature:
neoisoliquiiritin is a white crystalline solid, odorless. It is soluble in water and slightly soluble in ethanol and chloroform. Its chemical structure contains a diterpene acid (glycyrrhetic acid) bound to a glucose molecule.
Use:
neoisoliquiiritin has a wide range of applications in the pharmaceutical and health care industry. It has anti-inflammatory, anti-oxidant, anti-viral, anti-tumor and immune-enhancing effects. It is often used to treat inflammatory diseases such as hepatitis, gastritis, peptic ulcers and bronchitis. In addition, neoisoliquiiritin can also be used to improve the taste of food and beverages, and can be used as an ingredient in skin care products, with anti-aging and whitening effects.
Preparation Method:
neoisoliquiiritin is generally extracted from licorice root. The extraction process typically includes the steps of discoloration, crushing, percolation, precipitation, washing, and drying.
Safety Information:
neoisoliquiiritin is generally safe at recommend dosages. However, long-term or high-dose use may cause some side effects, such as water retention, sodium retention, and hypokalemia. In addition, overuse may also lead to problems such as high blood pressure, arrhythmia and osteoporosis. Neoisoliquitin should be used with caution in pregnant women, lactating women and patients with severe liver or kidney problems. Before use, it is best to consult a doctor or professional for advice.
Last Update:2024-04-09 20:52:54